Description
Decapeptide-12 (200mg) – Research-Grade Tyrosinase Inhibitor
SKU: DP12-200MG
Price: $248.60
Shipment: Ships same day if ordered by 12 PM PST.
This is Decapeptide-12. Think of it as a precision tool for researchers studying skin pigmentation pathways. The target is the tyrosinase enzyme, a key catalyst in melanin production. This 12-amino acid sequence is built to engage that target.
We stock the 200mg vial. It’s pure, documented, and ready for your lab. The sequence is Tyr-Arg-Ser-Aar-Lysd-Tyr-Ser-Ser-Trp-Tyr (Molecular Weight: 1311.46 g/mol). You get what’s on the label.
What Does The Research Say?
Published studies focus on Decapeptide-12’s role in modulating pigmentation. The mechanism is understood to involve binding to tyrosinase, potentially inhibiting its activity and affecting melanin synthesis.
- Melasma & Photodamage Models: One clinical study noted a 100% reduction in hyperpigmentation in 40% of test subjects after 12 weeks. Subjects with severe (grade 4) photodamage showed improvement to grade 3.
- Solar Lentigines: Research suggests potential clearance in a significant portion of cases, with many subjects showing improvement after 24 weeks of exposure.
- Penetration: The native peptide has a lyophobic structure. Modified versions (e.g., with a palmitate chain) have been studied to enhance lipophilicity and epidermal penetration while maintaining inhibitory activity.
- Cellular Metabolism: In-vitro studies on keratinocyte progenitors indicate Decapeptide-12 may upregulate sirtuin genes (SIRT1, SIRT3, SIRT6), which are involved in cellular stress resistance, metabolism, and DNA repair pathways.
The data is in the journals. Our job is to supply the exact material used in that research.
Specifications & Handling
Sequence: Tyr-Arg-Ser-Aar-Lysd-Tyr-Ser-Ser-Trp-Tyr
Molecular Formula: C65H90N18O17
Molecular Weight: 1311.46 g/mol
Synonyms: 137665-91-9
Important Notice: This product is for research use only in a controlled laboratory setting. It is a chemical for in-vitro experimentation. It is NOT for human or animal consumption, diagnostic use, or therapeutic application. All buyers must be licensed professionals or qualified researchers adhering to all applicable laws and regulations. By purchasing, you confirm you understand and agree to these terms.
References: Kassim et al., J Cosmet Laser Ther. 2012; Jiang et al., J Clin Aesthet Dermatol. 2018; Ramírez et al., J Drugs Dermatol. 2013; Hantash & Jimenez, J Drugs Dermatol. 2012; Bhatia et al., J Drugs Dermatol.
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