Description
MOTS-c (10mg) – Research Peptide
Price: $108.90
All orders ship same day if placed by 12 PM PST.
Here’s the straight data on MOTS-c. Think of it as a signaling molecule that comes directly from your cell’s power plants, the mitochondria. It’s a 16-amino acid peptide, officially a Mitochondrial-Derived Peptide (MDP). The research is new and compelling, pointing to its role as a systemic communicator for energy regulation and metabolic function.
We’re talking about a potential key player in how the body manages fuel. The science suggests MOTS-c may activate the AMPK pathway—a central regulator for cellular energy. When AMPK is engaged, cells ramp up their uptake of glucose and fatty acids to burn for energy. In lab studies, this has been observed to support a shift in fat metabolism, promoting the healthier brown fat and reducing white adipose tissue accumulation, particularly in models of diet-induced obesity.
But it doesn’t stop at fat. The research indicates a significant effect on skeletal muscle. MOTS-c appears to help muscle cells improve their glucose uptake, independent of insulin pathways. This is a big deal for studying metabolic flexibility. The result in models has been improved glucose tolerance and a counteraction of age-related insulin resistance in muscle tissue.
Further lab work points to broader systemic support. Studies note potential benefits for bone density by promoting type I collagen synthesis in osteoblasts. Other research observes a correlation between MOTS-c levels and healthy endothelial function, which is critical for cardiovascular research. There’s also emerging data on its role in cellular stress response and physical capacity in models, suggesting an influence on overall metabolic homeostasis and resilience.
In short, for the researcher looking into metabolism, obesity, diabetes, muscle function, or aging, MOTS-c represents a novel and powerful mitochondrial signal worth investigating. The mechanism is distinct, acting through pathways like AMPK and TGF-β/Smad to exert potential effects across multiple systems.
Specifications:
- Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Molecular Formula: C101H152N28O22S2
- Molecular Weight: 2174.64 g/mol
- Purity: >99% (by HPLC)
- Format: Lyophilized powder in sterile vial.
⚠️ IMPORTANT NOTICE
This product is sold for LABORATORY RESEARCH USE ONLY in a controlled environment for in-vitro testing. It is NOT for human or veterinary use, nor for introduction into any living organism. It is not a drug, dietary supplement, or cosmetic. All buyers must be verified, licensed researchers and/or qualified professionals. By purchasing, you attest that you understand the intended legal use and will handle the material according to all applicable local, state, and federal laws. The information presented is a summary of available scientific literature for educational purposes and does not constitute medical advice or a product claim.
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