Description
Nonapeptide-1 (Melanostatine-5) | 200mg Research Peptide
Look, here’s the deal. You’re after a potent, research-grade MC1R antagonist. This is it. Nonapeptide-1 isn’t some vague compound; it’s a specific, nine-amino-acid sequence (Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val) engineered for high-affinity binding. Think of it as a precision tool for investigating melanin regulation pathways in a laboratory setting.
The science is straightforward. In research models, alpha-MSH signals through the MC1R receptor to ramp up melanin production. Nonapeptide-1 is shown to block that signal. It sits in the receptor, preventing the activation cascade that leads to tyrosinase activity and pigment synthesis. Published data indicates it may also downregulate the receptor and key proteins like MITF, TRP-1, and TRP-2. The result in experimental models is a measurable reduction in melanin output.
We stock this at 200mg of >99% purity. The sequence is verified, the vial is sealed, and it ships with full documentation. This is for controlled, in-vitro research into skin pigmentation mechanisms. Period.
Product Specifications:
- Purity: >99% (HPLC Verified)
- Quantity: 200mg
- Sequence: Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NHâ‚‚
- Molecular Formula: C61H87N15O9S
- Molecular Weight: 1206.52 g/mol
- Synonyms: Melanostatine-5, Oxytocin Intermediate-nine peptide
Key Research Context:
Studies cite Nonapeptide-1 as one of the most potent MC1R inhibitors identified from screening tens of thousands of compounds. Research focuses on its mechanism for disrupting melanogenesis. Animal model data suggests potential for reducing pigmentation. Other research explores MC1R’s role in cell proliferation, noting that receptor inhibition can slow growth in certain melanoma cell lines. Nonapeptide-1’s structural affinity suggests it could be a relevant compound for such investigative work, though direct studies are needed.
Shipping: Orders placed before 12 PM PST ship same day. Domestic USA only.
ATTENTION: This product is sold exclusively as a research chemical. It is for laboratory in-vitro and experimentation use only by qualified, licensed professionals. It is NOT for human or animal consumption, diagnostic use, or therapeutic application. The purchase of this product constitutes agreement to our terms and conditions. You affirm you are authorized to handle such materials in a controlled laboratory environment. All information presented is for educational and scientific reference purposes.
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